How to deal with issues surrounding extremely expensive medicines in a just way? Who determines the prices, who pays them and who has access to such therapies? The German Ethics Council is holding its annual meeting at the Hotel Estrel in Berlin and via livestream on 22 June 2022, 10 a.m. to 6 p.m. Both with experts and the general public, the ethical challenges are discussed that arise when high-priced new medicines are used in a context of limited resources. One aim is to identify reasonable criteria for a sustainable and fair assessment, pricing and distribution of these drugs.