Prof. Dr. rer. nat.

Ursula Klingmüller

German Cancer Research Center

Focus of the Commitment in the German Ethics Council

  • Systems Biology
  • Systems Medicine
  • Personalised Medicine
  • Basic Research

Contact for Press Enquiries on the Following Topics

  • Systems Biology
  • Systems Medicine

Born in 1964

Professional Background

  • Since 2011 Professor for Systems Biology of Signal Transduction at the University of Heidelberg
  • Since 2007 Head of the Division of Systems Biology of Signal Transduction at the German Cancer Research Center (DKFZ) in Heidelberg
  • 2006 Refusal of a call for a professorship in Quantitative Systems Biology from Chalmers University of Technology in Gothenburg (Sweden)
  • 2004 Venia legendi in Cell Biology at the University of Heidelberg
  • 2003-2007 Leader of the Theodor Boveri Junior Research Group at the German Cancer Research Center (DKFZ) in Heidelberg
  • 2003 Refusal of a call for a professorship from the Technical University of Aachen
  • 2000 Habilitation and venia legendi in Molecular Biology and Genetics at the University of Freiburg
  • 1996-2003 Group Leader of a Hans Spemann Junior Research Group at the Max Planck Institute of Immunobiology in Freiburg
  • 1993-1996 Postdoctoral Fellow at the Whitehead Institute for Biomedical Research in Cambridge (USA)
  • 1992-1996 Postdoctoral Fellow at the Harvard Medical School in Boston (USA)
  • 1992 PhD (Dr. rer. nat.) at the University of Heidelberg
  • 1983-1988 Studies at the Universities of Bayreuth and Heidelberg and Diploma in Biology at the University of Heidelberg

Memberships

  • Since 2016 Member of the German Ethics Council
  • Member of the German Society for Cell Biology
  • Member of the German Society of Proteome Research
  • Member of the German Society for Lung Research
  • Member of the Executive Committee of the funding programs "Artificial Liver" and "LiSyM" issued by the Federal Ministry of Education and Research
  • Member of the Scientific Council of the Centre for Systems Biology in Groningen/Netherlands
  • Member of the Scientific Council BREAST in Dublin/Ireland
  • Chair of the Executive Women of the German Cancer Research Center (DKFZ) in Heidelberg
  • Member of the Selection Committee of the Karl-Heinz Beckurts Prize
  • Member of the SystemsX.ch Expert Group
  • 2007-2015 Member of the Board of Trustees of the German Cancer Research Center (DKFZ) in Heidelberg

Distinctions

  • 2012 Member of the Hinterzarten Circle for Cancer Research of the German Research Foundation
  • 1997 FEBS Anniversary Award

Publications (Selection)

  • Mueller, S. et al. (2015): T160-phosphorylated CDK2 defines threshold for HGF dependent proliferation in primary hepatocytes. In: Molecular Systems Biology, 11, 795.
  • Bachmann, J. et al. (2011): Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range. Molecular Systems Biology, 7, 516.
  • Becker, V. et al. (2010): Covering a broad dynamic range – information processing at the erythropoietin receptor. In: Science, 328 (5984), 1404-1408.
  • Swameye, I. et al. (2003): Identification of nucleocytoplasmic cycling as a remote sensor in cellular signaling by data-based dynamic modeling. In: Proceedings of the National Academy of Sciences oft he United States of America, 100, 1028-1033.
  • Klingmüller, U. et al. (1995): Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals. In: Cell, 80, 729-738.